Genome Plasticity in Health and Disease (Paperback)

Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Translational and Applied Genomics
Release date:	April 2020
First published:	2020
Volume editors:	Diego A. Forero • George P Patrinos
Dimensions:	235 x 191mm (L x W)
Format:	Paperback
Pages:	288
ISBN-13:	978-0-12-817819-5
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA Promotions
LSN:	0-12-817819-1
Barcode:	9780128178195

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