Cytokines and Colony Stimulating Factors - Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2003)

The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones. The roots of immunologic investigations reach far into the past. In 430 BC, Thucydides reported that survivors of the plague did not present a second time with similar symptoms. The first report of a successful immu- therapy was made by Edward Jenner in 1798 who found a protective effect of cowpox vaccination against human pox. Since then, much knowledge has been accumulated; today, investigations of the molecular mechanisms of immune regulation are of central research interest. The novel insights into gene polymorphisms and gene regulation gathered from this work has improved our knowledge of individual immune reactions and risk factors in overcoming infections. Strategies to use the immune system for cancer treatment have been propelled by the discovery of divergent immunoregulatory cytokines and the introduction of new gene therapy strategies to modify immune responses. Recently, the discovery of various dendritic cells has focused attention on these cell types as central elements of the immune response and to the possibility of dendritic cell expansion, maturation, and consecutive stimulation with immuno- active tumor-specific peptides. Similarly, methods for ex vivo expansion of various stem cell-derived cell types have led to an improved therapeutic management of various benign and malignant diseases.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 215
Release date:	November 2010
First published:	2003
Editors:	Dieter Koerholz • Wieland Kiess
Dimensions:	229 x 152 x 28mm (L x W x T)
Format:	Paperback
Pages:	478
Edition:	Softcover reprint of hardcover 1st ed. 2003
ISBN-13:	978-1-61737-318-3
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	1-61737-318-4
Barcode:	9781617373183

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!