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Extracellular Matrix in Development (Hardcover, 2013 Ed.)
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Extracellular Matrix in Development (Hardcover, 2013 Ed.)
Series: Biology of Extracellular Matrix
Expected to ship within 12 - 17 working days
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Cells in the developing embryo depend on signals from the
extracellular environment to help guide their differentiation. An
important mediator in this process is the extracellular matrix --
secreted macromolecules that interact to form large protein
networks outside the cell. During development, the extracellular
matrix serves to separate adjacent cell groups, participates in
establishing morphogenic gradients, and, through its ability to
interact directly will cell-surface receptors, provides
developmental clocks and positional information. This volume
discusses how the extracellular matrix influences fundamental
developmental processes and how model systems can be used to
elucidate ECM function. The topics addressed range from how ECM
influences early development as well as repair processes in the
adult that recapitulate developmental pathways. The series Biology
of Extracellular Matrix is published in collaboration with the
American Society for Matrix Biology.
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