This book presents the essentials of behavioral test methodology
needed for effective study planning and high quality behavioral
data collection on laboratory mice. The broad scope of behavioral
testing in relation to the neurosciences is discussed, as are
thefine details of varioustest situations. Mistakes made in past
research are scrutinized and lessons are drawn about how to avoid
them in future work. Diverse factors that can influence the results
of behavioral experiments are discussed, ranging from the specific
parameters employed in a test to the laboratory environment outside
the test situation itself. Throughout the book, emphasis is placed
on special issues that arise when testing genetically different
mice, including inbred strains and mice with targeted mutations.
This knowledge will assist an investigator who lacks formal
training in behavioral psychology to build a behavioral testing lab
and insure that its output meets current standards of good practice
in behavioral neuroscience research.
The book will be a convenient manual of procedures for daily use
in studies of mouse behavior. It will be of interest even to
experienced behavioural researchers, but of particular value to
scientists just beginning work with mice, including undergraduate
and graduate students as well as postdoctoral investigators who
want to collect phenotypic data with knockout and other genetically
defined mice. Constructed from materials used in a long running
course on Advanced Animal Behavior at University of North
Carolina-Greensboro, the book is an ideal text for a course on
behavioral testing.
A guide to running a behavioral testing lab, including the many
aspects of mouse research beyond the confines of the specific
testDiagrams and photographs are shown for many kinds of apparatus
and test situations with sufficient details such as dimensions to
enable building of replicasProvides step-by-step instructions on
planning and executing behavioral experiments in order to run them
successfullyA companion website will provide access to statistical
utilities in Excel and test protocols, examples of real documents
used for published studies, and video clips of the mice behaviors
resulting from various tests"
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