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Books > Medicine > Nursing & ancillary services > Biomedical engineering
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Drug Delivery - Materials Design and Clinical Perspective (Hardcover, 2014 ed.)
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Drug Delivery - Materials Design and Clinical Perspective (Hardcover, 2014 ed.)
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Current pharmaceutical and clinical approaches to the treatment of
disease suffer from the inherent limitations in the specialization
of drugs introduced to physiological systems. The interface of
clinical and material sciences has allowed for a broad spectrum of
creative approaches with the potential to alleviate these
shortcomings. However, the synergy of these disciplines also
presents problems in which nascent technology lacks the necessary
evaluation within its intended clinical environment. Given the
growing potential for materials science to address a number of
unanswered therapeutic needs, it remains even more pressing to
validate emerging drug delivery technologies in actual clinical
environments. Drug Delivery: Materials Design and Clinical
Perspective addresses the core fundamentals of drug delivery using
material science and engineering principles, and then applies this
knowledge using prominent examples from both the scientific
literature and clinical practice. Each chapter focuses on a
specific drug delivery technology, such as controlled-release
materials, thin-film materials, or smart materials. Within each
chapter, an initial section on "Engineering Concepts" reviews the
relevant fundamental principles that guide rational design. The
following section on "Materials Design" discusses how the design
process applies engineering concepts for use in physiological
systems. A third section on "Implementation" discusses current
approaches in the literature which have demonstrated effective drug
delivery in controlled environments. Finally, each chapter contains
several sections on "Clinical Applications" which describe the
validity of materials approaches from a clinical perspective; these
sections review the safety and efficacy of drug delivery systems
for specific, compelling medical applications. The book thereby
bridges materials science with clinical medicine, and provides the
reader with a bench-to-bedside view of novel drug delivery systems.
* Provides a comprehensive description of drug delivery systems
from a materials perspective * Includes a wide-ranging discussion
of clinical applications of drug delivery systems * Presents
separate chapters on controlled release materials, thin film
materials, self-microemulsifying materials, smart materials, etc. *
Covers fundamental engineering principles, rational materials
design, implementation testing, and clinical applications for each
material type
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