The Long and Short Non-coding RNAs in Cancer Biology (Hardcover, 1st ed. 2016)

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

General

Imprint:	Springer Verlag, Singapore
Country of origin:	Singapore
Series:	Advances in Experimental Medicine and Biology, 927
Release date:	July 2016
First published:	2016
Editors:	Erwei Song
Dimensions:	235 x 155 x 33mm (L x W x T)
Format:	Hardcover
Pages:	458
Edition:	1st ed. 2016
ISBN-13:	978-981-10-1496-3
Categories:	Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	981-10-1496-5
Barcode:	9789811014963

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