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The Long and Short Non-coding RNAs in Cancer Biology (Hardcover, 1st ed. 2016)
Loot Price: R2,766
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The Long and Short Non-coding RNAs in Cancer Biology (Hardcover, 1st ed. 2016)
Series: Advances in Experimental Medicine and Biology, 927
Expected to ship within 12 - 17 working days
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The book conveys a comprehensive knowledge of long and short ncRNAs
in cancer regulation and their potentials as diagnostic biomarkers
and therapeutic targets. Topics covered include the molecular
mechanisms of various classes of ncRNAs (with emphasis on long
non-coding RNAs and microRNAs) in cancer, the functional roles of
ncRNAs in regulating different cancer hallmarks (including
proliferation, apoptosis, stem-cell properties,
epithelial-mesenchymal transition, metabolism, angiogenesis,
tumor-host interactions and therapeutic resistance), the role of
ncRNAs in regulating cancer signaling circuitry programs
(highlighting their involvement in c-myc, p53 and NFkB signaling),
a systemic summary of clinical and preclinical studies that
evaluate the potential of ncRNA signatures for cancer diagnosis and
prognosis and strategies to delivery short ncRNAs as therapeutic
molecules for cancer treatment. This book may serve as a
comprehensive resource for researchers, graduate students and
oncologists in ncRNA and cancer research and help drug development
by identifying ncRNA targets.
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