Some of the current concepts used in transgenic research, an
increasingly important tool to study the regulation and function of
genes, are illustrated in this book. With these techniques, animal
models can be used to study human diseases; this opens up new
possibilities in both applied and basic research. Specifically, the
ability to introduce genes into the germline of mice and the
successful expression of the inserted gene within an organism
provide new insights and opportunities for biomedical research. The
discussion here shows how a detailed analysis of the underlying
molecular mechanisms will provide new insights into the genetic
origin of certain diseases and will lead to a better understanding
of normal and abnormal physiological processes.
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