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Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical)
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Bacillus thuringiensis Biotechnology (Hardcover, 2012)
Loot Price: R7,141
Discovery Miles 71 410
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Bacillus thuringiensis Biotechnology (Hardcover, 2012)
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Bacillus thuringiensis (Bt) has been used as a biopesticide in
agriculture, forestry and mosquito control because of its
advantages of specific toxicity against target insects, lack of
polluting residues and safety to non-target organisms. The
insecticidal properties of this bacterium are due to insecticidal
proteins produced during sporulation. Despite these ecological
benefits, the use of Bt biopesticides has lagged behind the
synthetic chemicals. Genetic improvement of Bt natural strains, in
particular Bt recombination, offers a promising means of improving
efficacy and cost-effectiveness of Bt-based bioinsecticide products
to develop new biotechnological applications. On the other hand,
the different Bacillus species have important biotechnological
applications; one of them is carried out by producing secondary
metabolites, which are the study object of natural product
chemistry. The amazing structural variability of these compounds
has attracted the curiosity of chemists and the biological
activities possessed by natural products have inspired the
pharmaceutical industry to search for lead structures in microbial
extracts. Screening of microbial extracts reveals the large
structural diversity of natural compounds with broad biological
activities, such as antimicrobial, antiviral, immunosuppressive,
and antitumor activities that enable the bacterium to survive in
its natural environment. These findings widen the target range of
Bacillus spp., in special B. thuringiensis, besides insecticidal
activity and help people to better understand its role in soil
ecosystem.
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