Bacteria in various habitats are subject to continuously changing
environmental conditions, such as nutrient deprivation, heat and
cold stress, UV radiation, oxidative stress, dessication, acid
stress, nitrosative stress, cell envelope stress, heavy metal
exposure, osmotic stress, and others. In order to survive, they
have to respond to these conditions by adapting their physiology
through sometimes drastic changes in gene expression. In addition
they may adapt by changing their morphology, forming biofilms,
fruiting bodies or spores, filaments, Viable But Not Culturable
(VBNC) cells or moving away from stress compounds via chemotaxis.
Changes in gene expression constitute the main component of the
bacterial response to stress and environmental changes, and involve
a myriad of different mechanisms, including (alternative) sigma
factors, bi- or tri-component regulatory systems, small non-coding
RNA s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin
systems, the stringent response, efflux pumps, alarmones, and
modulation of the cell envelope or membranes, to name a few. Many
regulatory elements are conserved in different bacteria; however
there are endless variations on the theme and novel elements of
gene regulation in bacteria inhabiting particular environments are
constantly being discovered. Especially in (pathogenic) bacteria
colonizing the human body a plethora of bacterial responses to
innate stresses such as pH, reactive nitrogen and oxygen species
and antibiotic stress are being described. An attempt is made to
not only cover model systems but give a broad overview of the
stress-responsive regulatory systems in a variety of bacteria,
including medically important bacteria, where elucidation of
certain aspects of these systems could lead to treatment strategies
of the pathogens. Many of the regulatory systems being uncovered
are specific, but there is also considerable cross-talk between
different circuits. Stress and Environmental Regulation of Gene
Expression and Adaptation in Bacteria is a comprehensive two-volume
work bringing together both review and original research articles
on key topics in stress and environmental control of gene
expression in bacteria. Volume One contains key overview chapters,
as well as content on one/two/three component regulatory systems
and stress responses, sigma factors and stress responses, small
non-coding RNAs and stress responses, toxin-antitoxin systems and
stress responses, stringent response to stress, responses to UV
irradiation, SOS and double stranded systems repair systems and
stress, adaptation to both oxidative and osmotic stress, and
desiccation tolerance and drought stress. Volume Two covers heat
shock responses, chaperonins and stress, cold shock responses,
adaptation to acid stress, nitrosative stress, and envelope stress,
as well as iron homeostasis, metal resistance, quorum sensing,
chemotaxis and biofilm formation, and viable but not culturable
(VBNC) cells. Covering the full breadth of current stress and
environmental control of gene expression studies and expanding it
towards future advances in the field, these two volumes are a
one-stop reference for (non) medical molecular geneticists
interested in gene regulation under stress.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
