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Disorders of the Monocyte Macrophage System - Pathophysiological and Clinical Aspects (Paperback)
Loot Price: R1,576
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Disorders of the Monocyte Macrophage System - Pathophysiological and Clinical Aspects (Paperback)
Series: Haematology and Blood Transfusion Hamatologie und Bluttransfusion, 27
Expected to ship within 10 - 15 working days
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The origin and function of normal monocytes and macrophages have
been clearly defined by extensive investigations in human and in
animal models. The central importance ofthis cell system for the
biological defense mecha- nisms is well established: phagocytosis,
inactivation and destruction of organic and inorganic materials, an
important role in the initiation ofhumo- ral and cell mediated
immunological responses, and the secretion of a varie- ty of
chemical mediator and effector substances are the most important
fea- tures of this ontogenetically ancient cell system. However,
the data on this cellular system are rather recent, and this may
explain why relatively little attention has been payed to the
pathology of the monocyte-macrophage system (MMS) until now. In
addition, this monograph should focus attention on the secondarypa-
thophysiological implications of the MMS in disorders not primarily
origi- nating from this system. Several techniques are available to
identify even abnormal individuals of this cell system and,
therefore, can be employed for the study of severely altered or
neoplastic monocytic cells.
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