|
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
|
Buy Now
Immune System Modelling and Simulation (Paperback)
Loot Price: R1,563
Discovery Miles 15 630
|
|
|
Immune System Modelling and Simulation (Paperback)
Expected to ship within 12 - 19 working days
|
The book describes a computational model of the immune system
reaction, C-ImmSim, built along the lines of the computer model
known as the Celada-Seiden model (CS-model). The computational
counterpart of the CS-model is called IMMSIM which stands for
IMMune system SIMulator. IMMSIM was written in 1992 by the
physicist Phil E. Seiden and the immunologist Franco Celada. This
model was built around the idea of developing a computerized system
to perform experiments similar in vivo experiments; a tool
developed to help biologists testing theories and hypothesis about
how the immune system works. C-ImmSim is best viewed as a
collection of models in a single program. It incorporates the
principal core facts of today's immunological knowledge, such as
the diversity of specific elements, MHC restriction, clonal
selection, thymic education of T cells, antigen processing and
presentation (both the cytosolic and endocytic pathways are
implemented), cell-cell cooperation, homeostasis of cells created
by the bone marrow, hyper mutation of antibodies, maturation of the
cellular and humoral response, and memory. Besides, an antigen can
represent a bacterium, a virus, or an allergen or a tumor cell.
C-ImmSim has been recently customized to simulate the HIV-1
infection. Moreover, it can simulate the immunotherapy for cancer.
These features are all present in the code and people can choose to
turn them on and off at compiling time. The book presents the basic
model as well as the various customizations to implement the
description of different diseases and the way they have been used
in practice to produce new knowledge either from hypothesis or from
lab-experiment data. In this respect, the book can be used as a
practical guide to implement a computational model with which to
study a specific disease and to try to address realistic clinical
questions.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
