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Computational Cardiology - Modeling of Anatomy, Electrophysiology, and Mechanics (Paperback, 2004 ed.)
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Computational Cardiology - Modeling of Anatomy, Electrophysiology, and Mechanics (Paperback, 2004 ed.)
Series: Lecture Notes in Computer Science, 2966
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Biomedical research is at a critical point at present. The research
has led to an enormous amount of data and models describing these
data, but - proachesforapplication,formalizationand integrationof
this knowledgefrom the molecular to the system level are still
topics of ongoing research and c- tainly far from fully developed.
Also in cardiology the di?erent anatomical and physiological
constituents as well as the coupling between them are being
researchedin increasing detail and areoften described using
computer-based models. But for this domain an integrative framework
is still missing. The application of computer-based modeling as a
research, development and clinical tool often necessitates the
coupling of various models from di?- ent levels. Describing the
interactions between these models, which are both physically sound
and computationally e?cient, determines the applicability of such
promising computer-based attempts.
Myhopeisthatthisbookwillcontributetothecomprehension,spreadand
impact of computer-based modeling in cardiology,both from a
teaching point of view and by summarizing knowledge from several,
commonly delimited topics relating to the cardiac manifoldness. The
book evolved from revision and extension of my professorial disser-
tion(Habilitationsschrift)"MathematicalModelingoftheMammalianHeart"
written in 2002. This dissertation was based on notes for the
lectures "C- putational Biology: Bioelectromagnetism and
Biomechanics," "Simulation of Physical Fields in the Human Body,"
and "Anatomical, Physical and Fu- tional Models of the Human Body,"
which I gaveat the Universita t Karlsruhe (TH) from 1998 to 2003.
Salt Lake City, 1 February 2004 Frank B. Sachse VI Preface
Acknowledgement Manypeople meritmy gratitudefor their
assistanceandsupportin this work.
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