Histological Typing of Tumours of the Exocrine Pancreas (Paperback, Softcover reprint of the original 2nd ed. 1996)

This is a histological classification of tumours and tumour-like lesions of the exocrine pancreas which also includes those tu- mours showing a mixture of exocrine and endocrine elements. The classification is based principally on standard microscopic observations, but whenever indicated it incorporates diagnosti- cally valuable immunohistological findings. In addition, the most important immunohistological findings which are helpful in cat- egorizing pancreatic tumours are summarised in Table 1. The major guideline of this classification scheme is the group- ing of the pancreatic exocrine tumours according to their biologi- cal behaviour. Thus, the neoplasms are broadly divided into benign (adenoma) and malignant tumours (carcinoma). How- ever, in recent years we have learned that this division is not a sharp but rather a gradual transition. We therefore added a third group which we call "tumours of uncertain malignant potential" representing a borderline category analogous to that recognized for some ovarian tumours. This group includes mucinous cystic tumour, intraductal papillary-mucinous tumour and solid- pseudopapillary tumour. These neoplasms are defined by the grade of dysplasia and/or potential to become malignant. Mucinous cystic tumours of uncertain malignant potential, for instance, exhibit moderate epithelial dysplasia, but do not show severe dysplasia/carcinoma in situ changes, nor carcinomatous invasion of the cyst wall or the adjacent pancreatic tissue. Solid- pseudopapillary tumour has a benign looking histological ap- pearance, but metastases may occur. Biologically, all these neoplasms are primarily slow-growing lesions and have an excel- lent prognosis when adequately treated by complete resection.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	WHO. World Health Organization. International Histological Classification of Tumours
Release date:	2001
First published:	April 1998
Authors:	G. Kloppel • E. Solcia • D.S. Longnecker • C. Capella • Leslie H. Sobin
Dimensions:	242 x 170 x 5mm (L x W x T)
Format:	Paperback
Pages:	61
Edition:	Softcover reprint of the original 2nd ed. 1996
ISBN-13:	978-3-540-60280-4
Categories:	Books > Medicine > Clinical & internal medicine > Gastroenterology Books > Science & Mathematics > Science: general issues > Scientific nomenclature & classification Books > Medicine > Other branches of medicine > Pathology > Histopathology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	3-540-60280-1
Barcode:	9783540602804

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