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Complications of Cancer Chemotherapy - Proceedings of the Plenary Sessions of E.O.R.T.C., Paris, June 1973 (Paperback, Softcover reprint of the original 1st ed. 1974)
Loot Price: R2,919
Discovery Miles 29 190
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Complications of Cancer Chemotherapy - Proceedings of the Plenary Sessions of E.O.R.T.C., Paris, June 1973 (Paperback, Softcover reprint of the original 1st ed. 1974)
Series: Recent Results in Cancer Research, 49
Expected to ship within 10 - 15 working days
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Total price: R2,939
Discovery Miles: 29 390
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G. MATHE and R. K. OLDHAM' Institut de Cancerologie et d'Immunogem
tique, Hopital Paul Brousse, Villejuif Since the last war, cancer
chemotherapy has been the object of very intensive and expensive
research. Nevertheless, its development has been very slow, and its
ultimate potential is today somewhat in doubt. In doubt because it
does not cure any cancer patients except a) females carrying
placental choriocarcinoma, a semi-allogenic tumor, in which case,
cure may be in fluenced by immune rejection, and b) children
suffering from Burkitt's tumor, where the probable reason for the
cure is that all the neoplastic cells are in the cycle, which is a
unique condition among all the human tumor varieties. Whether the
long term survivors in acute leukemia, lymphomas, certain sarcomas
and certain testicular tumors are "cures" will require longer
follow-up. The idea that chemotherapy does not cure most cancer
patients because all their neoplastic cells are not in cycle has
led to the use of drug combinations. Whatever they are, "cocktail
combinations" which are made up of drugs given according to any
timing, or scientific combinations, based on pharmacodynamics,
pharmaco kinetics or cell kinetics data, are more toxic than single
drugs, and are all the more toxic as the number of drugs in the
combination is increased."
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