Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Designer Receptors Exclusively Activated by Designer Drugs (Hardcover, 1st ed. 2015)
Loot Price: R2,740
Discovery Miles 27 400
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Designer Receptors Exclusively Activated by Designer Drugs (Hardcover, 1st ed. 2015)
Series: Neuromethods, 108
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This volume provides current methods to analyze the properties of
designer receptors exclusively activated by designer drugs
(DREADDs) in vitro and to measure the biological responses of
DREADD activation in different neuronal populations in vivo.
Chapters focus on the utility of DREADD technology to selectively
stimulate or inhibit neuronal activity in selected brain areas of
transgenic mice. In addition, the successful use of DREADD
expression in rats and Drosophila is described. Together, the
DREADD technology represents a non-invasive, chemical-genetic tool
for investigating neuronal signaling and the resulting behavioural
responses in vivo. Written in the popular Neuromethods series
style, chapters include the kind of detail and key advice from the
specialists needed to get successful results in your own
laboratory. Concise and easy-to-use, Designer Receptors Exclusively
Activated by Designer Drugs aims to ensure successful results in
the further study of this vital field.
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