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Bioorganometallic Chemistry (Paperback, Softcover reprint of hardcover 1st ed. 2006)
Loot Price: R5,409
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Bioorganometallic Chemistry (Paperback, Softcover reprint of hardcover 1st ed. 2006)
Series: Topics in Organometallic Chemistry, 17
Expected to ship within 10 - 15 working days
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Bioorganometallic Chemistry has become a mature area of science and
is comprehensively covered by leading experts in this book.
Naturally occuring bioorganometallic complexes, such as vitamin B12
and recently discovered iron and nickel hydrogenases, including a
possible role of the latter in the geochemical theory of the origin
of life, are considered. The possible formation of carbene
complexes of cytochrome P450 enzymes in various metabolisms of
xenobiotics is also discussed. The bioorganometallic chemistry is
considered to provide not only organometallic receptors such as
polynuclear organometallic macrocycles for biologically interesting
molecules but also ferrocene-peptide bioconjugates giving a
peptidomimetic basis for protein folding. The medicinal properties
of organometallic compounds are reviewed, with notable applications
in the treatment and diagnosis of cancer and in the treatment of
viral, fungal, bacterial and parasitic infections. Therefore the
reader will get a balanced view of this rapidly developing and
promising area.
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