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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Stem Cell Aging: Mechanisms, Consequences, Rejuvenation (Hardcover, 1st ed. 2015)
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Stem Cell Aging: Mechanisms, Consequences, Rejuvenation (Hardcover, 1st ed. 2015)
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Aging of somatic stem cells reduces cell function and results in
dysfunctional organs and tissues, making it an underlying cause of
diseases associated with aging. It might even be the primary cause
for age-associated attrition of tissue function in organs that
heavily rely on stem cells for maintaining homeostasis, like the
skin, blood and intestines. Understanding the molecular and
cellular mechanisms involved is critical for developing approaches
to attenuate stem cell aging and could pave the way for improved
quality of life among the elderly. Written by highly prominent
experts in the field, this book presents the current state of
knowledge on these mechanisms. It offers insights into stem cell
function, explains in detail the mechanisms of stem cell aging in
model organisms as well as mammalian systems and describes related
diseases and approaches to attenuating stem cell aging or achieving
rejuvenation. The book is intended for all scientists and
clinicians working with stem cells, aging mechanisms or age-related
diseases.
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