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Genetic Design Automation - A Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits (Paperback, 1st ed. 2020)
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Genetic Design Automation - A Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits (Paperback, 1st ed. 2020)
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This textbook introduces readers to the recent advances in the
emerging field of genetic design automation (GDA). Starting with an
introduction and the basic concepts of molecular biology, the
authors provide an overview of various genetic design automation
tools. The authors then present the DVASim tool (Dynamic Virtual
Analyzer and Simulator) which is used for the analysis and
verification of genetic logic circuits. This includes methods and
algorithms for the timing and threshold value analyses of genetic
logic circuits. Next, the book presents the GeneTech tool (A
technology mapping tool for genetic circuits) and the methods
developed for optimization, synthesis, and technology mapping of
genetic circuits. Chapters are followed by exercises which give
readers hands-on practice with the tools presented. The concepts
and algorithms are thoroughly described, enabling readers to
improve the tools or use them as a starting point to develop new
tools. Both DVASim and GeneTech are available from the developer's
website, free of charge. This book is intended for a
multidisciplinary audience of computer scientists, engineers and
biologists. It provides enough background knowledge for computer
scientists and engineers, who usually do not have any background in
biology but are interested to get involved in this domain. This
book not only presents an accessible basic introduction to
molecular biology, it also includes software tools which allow
users to perform laboratory experiments in a virtual in-silico
environment. This helps newbies to get a quick start in
understanding and developing genetic design automation tools. The
third part of this book is particular useful for biologists who
usually find it difficult to grasp programming and are reluctant to
developing computer software. They are introduced to the graphical
programming language, LabVIEW, from which they can start developing
computer programs rapidly. Readers are further provided with small
projects which will help them to start developing GDA tools.
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