The pace of new research and level of innovation repeatedly
introduced into the field of drug delivery to the lung is
surprising given its state of maturity since the introduction of
the pressurized metered dose inhaler over a half a century ago. It
is clear that our understanding of pulmonary drug delivery has now
evolved to the point that inhalation aerosols can be controlled
both spatially and temporally to optimize their biological effects.
These abilities include controlling lung deposition, by adopting
formulation strategies or device technologies, and controlling drug
uptake and release through sophisticated particle technologies. The
large number of contributions to the scientific literature and
variety of excellent texts published in recent years is evidence
for the continued interest in pulmonary drug delivery research.
This reference text endeavors to bring together the fundamental
theory and practice of controlled drug delivery to the airways that
is unavailable elsewhere. Collating and synthesizing the material
in this rapidly evolving field presented a challenge and ultimately
a sense of achievement that is hopefully reflected in the content
of the volume.
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