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The Science and Applications of Microbial Genomics - Workshop Summary (Paperback)
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The Science and Applications of Microbial Genomics - Workshop Summary (Paperback)
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Over the past several decades, new scientific tools and approaches
for detecting microbial species have dramatically enhanced our
appreciation of the diversity and abundance of the microbiota and
its dynamic interactions with the environments within which these
microorganisms reside. The first bacterial genome was sequenced in
1995 and took more than 13 months of work to complete. Today, a
microorganism's entire genome can be sequenced in a few days. Much
as our view of the cosmos was forever altered in the 17th century
with the invention of the telescope, these genomic technologies,
and the observations derived from them, have fundamentally
transformed our appreciation of the microbial world around us. On
June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on
Microbial Threats convened a public workshop in Washington, DC, to
discuss the scientific tools and approaches being used for
detecting and characterizing microbial species, and the roles of
microbial genomics and metagenomics to better understand the
culturable and unculturable microbial world around us. Through
invited presentations and discussions, participants examined the
use of microbial genomics to explore the diversity, evolution, and
adaptation of microorganisms in a wide variety of environments; the
molecular mechanisms of disease emergence and epidemiology; and the
ways that genomic technologies are being applied to disease
outbreak trace back and microbial surveillance. Points that were
emphasized by many participants included the need to develop robust
standardized sampling protocols, the importance of having the
appropriate metadata, data analysis and data management challenges,
and information sharing in real time. The Science and Applications
of Microbial Genomics summarizes this workshop. Table of Contents
Front Matter Workshop Overview Appendix A Appendix B--Agenda
Appendix C--Acronyms Appendix D--Glossary Appendix E--Speaker
Biographies
General
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