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Biochemical Sites of Insecticide Action and Resistance (Paperback, Softcover reprint of the original 1st ed. 2001)
Loot Price: R4,223
Discovery Miles 42 230
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Biochemical Sites of Insecticide Action and Resistance (Paperback, Softcover reprint of the original 1st ed. 2001)
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Total price: R4,233
Discovery Miles: 42 330
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In recent years many of the conventional methods of insect control
by broad spectrum synthetic chemicals have come under scrutiny
because of their unde sirable effects on human health and the
environment. In addition, some classes of pesticide chemistry,
which generated resistance problems and severely affected the
environment, are no longer used. It is against this background that
the authors of this book present up-to-date findings-relating to
biochemical sites that can serve as targets for developing
insecticides with selective prop erties, and as the basis for the
elucidation of resistance mechanisms and countermeasures. The book
consists of eight chapters relating to biochemical targets for
insec ticide action and seven chapters relating to biochemical
modes of resistance and countermeasures. The authors of the
chapters are world leaders in pesti cide chemistry, biochemical
modes of action and mechanisms of resistance. Biochemical sites
such as chitin formation, juvenile hormone and ecdysone receptors,
acetylcholine and GABA receptors, ion channels, and neuropeptides
are potential targets for insecticide action. The progress made in
recent years in molecular biology (presented in depth in this
volume) has led to the iden tification of genes that confer
mechanisms of resistance, such as increased detoxification,
decreased penetration and insensitive target sites. A combina tion
of factors can lead to potentiation of the resistance level.
Classifications of these mechanisms are termed gene amplification,
changes in structural genes, and modification of gene expression.
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