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Cyclic Nucleotides - Part I: Biochemistry (Paperback, Softcover reprint of the original 1st ed. 1982)
Loot Price: R2,969
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Cyclic Nucleotides - Part I: Biochemistry (Paperback, Softcover reprint of the original 1st ed. 1982)
Series: Handbook of Experimental Pharmacology, 58 / 1
Expected to ship within 10 - 15 working days
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The purpose of the present volume, the first of two on the
pharmacology, biochemistry, and physiology of cyclic nucleotides,
is to provide a comprehensive and up-to-date anthology on the
nature and role of these important chemical regulators. Each of the
chapters is the work of internationally known researchers who
present a lucid and detailed review of their subject and not merely
a single laboratory's viewpoint. The chapters emphasize critical
assessments of the field rather than mere listings of experimental
findings. By so doing, the contributors present the role of cyclic
nucleotides in relationship to other intracellular regulators. Each
chapter begins with a detailed summary to allow the reader to
obtain a rapid overview of subsequent material. In addition, there
are extensive bibliographies and a detailed subject index. Wherever
pertinent, the chapters contain sections on drug mechanisms,
physiological relevance, and disease processes. The Volume is
divided into two sections, each beginning with an overview written
by Professors T. W. RALL and P. GREENGARD, respectively. The first
section focuses on the detailed pharmacology and chemistry of
cyclic nucleotides, including their formation, degradation,
measurement, and interaction with various modulatory agents, such
as receptors and calcium. The second section is concerned with the
biochemistry of protein phosphorylation, a process which appears to
be one of the most important mechanisms for the intracellular
expression of cyclic nucleotide action in eukaryotic cells.
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