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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Coronary Blood Flow - Mechanics, Distribution, and Control (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R4,046
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Coronary Blood Flow - Mechanics, Distribution, and Control (Paperback, Softcover reprint of the original 1st ed. 1991)
Series: Developments in Cardiovascular Medicine, 124
Expected to ship within 10 - 17 working days
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by JULIEN IE HOFFMAN One of the earliest coronary physiologists was
Scaramucci who, in 1695, postu lated that during systole the
contracting myocardium inhibited coronary blood flow. Since then,
the many contributions that have been made to our knowledge of the
coronary circulation can be arbitrarily divided into three phases
based on advances in technical methods. The early phase of research
into the coronary circulation, done with great difficulty with
crude methods, may be regarded as ending in the 1940s, and it
included major discoveries made by such well known investigators as
Georg von Anrep, Ernest Starling, Carl Wiggers, and Louis Katz, who
formulated much of our basic understanding of the field. After
1940, the field of coronary physiology entered a new phase when
instruments for high fidelity registration of coronary flow and
pressure became available. This era was domi nated by Donald Gregg
who combined careful attention to the function of these instruments
(some of which he helped to develop) with an extraordinary ability
to discern mechanisms from apparently minor changes in coronary
flow and pressure patterns. His book 'The Coronary Circulation in
Health and Disease' set a new standard in the field. After 1960,
techniques for measuring regional myocardial blood flow became
available, and enabled a large group of eminent investigators to
make major advances in understanding the physiology and
pathophysiology of myocardial blood flow."
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