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Rubidomycin - A New Agent against Cancer (Paperback, Softcover reprint of the original 1st ed. 1969)
Loot Price: R1,519
Discovery Miles 15 190
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Rubidomycin - A New Agent against Cancer (Paperback, Softcover reprint of the original 1st ed. 1969)
Series: Recent Results in Cancer Research, 20
Expected to ship within 10 - 15 working days
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Trials in the treatment of the leukemias are sometimes based on a
hypothesis, as in the case of exchange transfusion [33] or the use
of antimetabolites [86]. Or they are conducted empirically as the
results of chance observations, as in the case of the use of the
nitrogen mustards, urethane, and the Vinca alkaloids. Or they lie
between the two, aiming at making use of well established
biological facts: examples are the use of ACTH, cortisone and, more
recently, the antibiotics. What is true for bacteria may also
perhaps be true, if not for elephants, at least for the malignant
cells of mammals. It was this idea that lay behind the first
attempts at treating cancer and leukemia with antibiotics. The
results obtained by the use of certain substances extracted from
micro-organisms (actinomycin, azaserine, mito mycin,
rufocromomycin), although encouraging at times, were inconsistent.
The action of rubidomycin appears to cover a wider spectrum and to
be more consistent and more effective. As in the case of Homer and
Christopher Columbus, the honor of having given birth to
rubidomycin is claimed by more than one country and town. In fact,
the same product was discovered in the same year, though quite
independently, by a group of French workers [184] who described it
under the name of rubidomycin, and by a group of Italian workers
[87] who studied it under the name of daunomycin.
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