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Neuropsychiatric Disorders and Epigenetics (Hardcover)
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Neuropsychiatric Disorders and Epigenetics (Hardcover)
Series: Translational Epigenetics
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Neuropsychiatric Disorders and Epigenetics is a comprehensive
reference for the epigenetic basis of most common neuropsychiatric
disorders. The volume is organized into chapters representing
individual neuropsychiatric disorders, from addition to obesity
contributed by leading experts in their respective fields. The
epigenetic aspects of each disorder are discussed, in the context
of the full range of epigenetic mechanisms including DNA
modification, histone post-translational modification, chromatin
organization and non-coding RNA. A particular emphasis is placed on
potential epigenetic interventions, when the effects of
environmental stimuli on epigenetic states is particularly relevant
o disease. Recent discoveries in epigenetic research enabled by
epic advances in genomic technologies have positioned the field for
broad translation to therapeutic interventions for previously
unmanageable disorders Neuropsychiatric disorders represent a prime
target of epigenetic interventions as they are highly debilitating,
often chronic diseases with enormous costs to society. Thus, this
volume will help define epigenetics as a key player in
neuropsychiatric disorders, highlighting the full spectrum of
epigenetic mechanisms underlying such disorders and introducing the
vast range of epigenetic therapies under development.
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