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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Standardization of Epidemiologic Studies of Host Susceptibility (Hardcover, 1994 ed.)
Loot Price: R3,852
Discovery Miles 38 520
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Standardization of Epidemiologic Studies of Host Susceptibility (Hardcover, 1994 ed.)
Series: NATO Science Series A:, 270
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The incidence of insulin-dependent diabetes mellitus (100M) varies
dramatically across racial groups and countries, with annual
age-adjusted rates of approximately 40/100,000 per year in Finland,
but only 0.51100,000 per year in China. Although reasons for these
marked geographic differences are unknown, it is likely that
genetic variations across populations play a m or role. To
determine the contribution of genetic factors to the global
patterns of 100M incidence, international comparative studies are
now being undertaken as part of the WHO Multinational Project for
Childhood Oiabetes, known as the DIAMOND Project. It is, therefore,
necessary to develop and implement epidemiologic standards for
these investigations which can be applied across populations. This
will ensure that comparable data are obtained in all countries, and
that relevant scientific questions can be properly addressed. The
development of standards for molecular epidemiologic studies of
100M is the of the NATO Advanced Research Workshop. During this
meeting at the objective University of Pittsburgh, scientists from
across the world convened to discuss issues relating to the
standardization of: 1. the collection of family history data to
assess the risk of 100M in first degree relatives, 2. case-control
molecular epidemiology studies of 100M susceptibility, 3. HLA
family studies, 4. laboratory methods and ONA technology transfer
for genetic marker evaluations.
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