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The Retroviridae (Hardcover, 1993 ed.)
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The Retroviridae (Hardcover, 1993 ed.)
Series: The Viruses
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Total price: R4,419
Discovery Miles: 44 190
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In this second volume in the series The Retroviridae, the readers
are treated to up-to-date reviews on these viruses, which are found
in a variety of animal species. The volume begins with important
observations on the general fea tures of retrovirus entry into
cells as determined by the viral envelope glyco proteins and the
cell surface receptors (Chapter 1). Aspects of this virus-cell
interaction form the basis for the variety of biologic effects
associated with this virus family. A timely review of the oncogenic
feline viruses is included next (Chapter 2). These viruses, along
with the avian and murine retroviruses (Volume 1, Chapters 6 and
7), have provided valuable insight into cancer induction in other
animal species, including humans. Two other major groups of
retroviruses, the lentiviruses and the spuma viruses, are
introduced in the present volume. Initially these groups, along
with oncoviruses, were the three subfamilies in the Retroviridae.
This com plex virus family has now been reclassified into seven
separate genera (Vol ume 1, Chapter 2). Equine infectious anemia
virus is the prototype for a lentivirus (Chapter 5). One of the
first viruses discovered in nature (1904), it was only relatively
recently recognized as a retrovirus. Lentiviruses are asso ciated
primarily with immunologic disorders such as autoimmunity and AIDS
(Chapters 3-5), but their association with neurologic disease is
also well established (Chapters 4 and 5, and future volumes)."
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