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Pharmacological Treatment of Alzheimer's Disease - Molecular & Neurobiological Foundations (Hardcover, New)
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Pharmacological Treatment of Alzheimer's Disease - Molecular & Neurobiological Foundations (Hardcover, New)
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In recent years, research on Alzheimer's disease has become one of
the most intensely pursued areas in the field of neuroscience.
Despite the wealth of information gathered, however, relatively
little of what has been learned has resulted in the development of
effective treatments.
Pharmacological Treatment of Alzheimer's Disease: Molecular and
Neurobiological Foundations gathers the top investigators in the
area of Alzheimer's research and presents their pioneering work on
potential treatments for this devastating disease. Combining
current knowledge of the neurobiology of memory with molecular
studies related to disease etiology, this book provides a
comprehensive review of the latest research on Alzheimer's as well
as a thorough examination of current experiments with drugs that
could correct the biochemical defects that cause Alzheimer's or
ameliorate the associated cognitive deficits. Each of the book's
three sections, "Neurobiology of Cognition," "Molecular Aspects of
Alzheimer's Disease," and "Alzheimer's Drug Discovery and
Development," is a collection of the most recent studies by
prominent specialists in their respective fields.
Among the numerous topics covered:
* Structure and dynamics of multiple memory systems in Alzheimer's
disease
* Interaction of neuromodulatory systems regulating memory
storage
* Neuropsychological features of Alzheimer's disease
* Normal brain aging and Alzheimer's disease pathology
* Recent developments in the genetics of Alzheimer's disease
* Animal models relevant to Alzheimer's disease
* Considerations for clinical trials in Alzheimer's disease
* A fundamental role for estrogens in cognition
andneuroprotection
* Alzheimer's disease: prospects for treatment in the next decade.
A comprehensive and balanced overview of the most critically
important information available, Pharmacological Treatment of
Alzheimer's Disease: Molecular and Neurobiological Foundations
heralds a new phase in the process of studying this uniquely human
disease: the search for treatments. It is must reading for
neuroscientists, pharmacologists, medicinal chemists, and academic
physicians involved in basic research and clinical trials, as well
as for clinicians who treat Alzheimer's patients.
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