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Frontiers in Computational and Systems Biology (Hardcover, 2010)
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Frontiers in Computational and Systems Biology (Hardcover, 2010)
Series: Computational Biology, 15
Expected to ship within 12 - 17 working days
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Biological and biomedical studies have entered a new era over the
past two decades thanks to the wide use of mathematical models and
computational approaches. A booming of computational biology, which
sheerly was a theoretician's fantasy twenty years ago, has become a
reality. Obsession with computational biology and theoretical
approaches is evidenced in articles hailing the arrival of what are
va- ously called quantitative biology, bioinformatics, theoretical
biology, and systems biology. New technologies and data resources
in genetics, such as the International HapMap project, enable
large-scale studies, such as genome-wide association st- ies, which
could potentially identify most common genetic variants as well as
rare variants of the human DNA that may alter individual's
susceptibility to disease and the response to medical treatment.
Meanwhile the multi-electrode recording from behaving animals makes
it feasible to control the animal mental activity, which could
potentially lead to the development of useful brain-machine
interfaces. - bracing the sheer volume of genetic, genomic, and
other type of data, an essential approach is, ?rst of all, to avoid
drowning the true signal in the data. It has been witnessed that
theoretical approach to biology has emerged as a powerful and st-
ulating research paradigm in biological studies, which in turn
leads to a new - search paradigm in mathematics, physics, and
computer science and moves forward with the interplays among
experimental studies and outcomes, simulation studies, and
theoretical investigations.
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