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Total Synthesis of (+/-)-Maoecrystal V (Paperback, Softcover reprint of the original 1st ed. 2014)
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Total Synthesis of (+/-)-Maoecrystal V (Paperback, Softcover reprint of the original 1st ed. 2014)
Series: Springer Theses
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Total price: R3,193
Discovery Miles: 31 930
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In this thesis, the author describes the total synthesis of natural
product Maoecrystal V in detail. In the first part of the thesis,
the author introduces the research background and reviews the
research progress in total synthesis of Maoecrystal V. In the
second part, the author develops a novel and concise approach for
the stereo selective construction of the tetracyclic model system
of Maoecrystal V. The model system is accomplished in 8 steps with
20% yield. In the third part, the author describes the first
successful total synthesis of Maoecrystal V and investigates four
strategies for constructing the key tetrahydrofuran oxa-bridge
skeleton. The total synthesis starts from a known compound and is
accomplished in 17 steps with 1.2% yield. The successful total
synthesis of Maoecrystal V will contribute to the development of
efficient synthetic strategies for natural products and other
compounds with complex structures.
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