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Books > Medicine > Clinical & internal medicine > Ophthalmology
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Retinal Degenerative Diseases - Mechanisms and Experimental Therapy (Paperback, Softcover reprint of the original 1st ed. 2018)
Loot Price: R8,403
Discovery Miles 84 030
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Retinal Degenerative Diseases - Mechanisms and Experimental Therapy (Paperback, Softcover reprint of the original 1st ed. 2018)
Series: Advances in Experimental Medicine and Biology, 1074
Expected to ship within 10 - 15 working days
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The blinding diseases of inherited retinal degenerations have no
treatments, and age-related macular degeneration has no cures,
despite the fact that it is an epidemic among the elderly, with 1
in 3-4 affected by the age of 70. The RD Symposium will focus on
the exciting new developments aimed at understanding these diseases
and providing therapies for them. Since most major scientists in
the field of retinal degenerations attend the biennial RD Symposia,
they are known by most as the "best" and "most important" meetings
in the field. The volume will present representative
state-of-the-art research in almost all areas of retinal
degenerations, ranging from cytopathologic, physiologic, diagnostic
and clinical aspects; animal models; mechanisms of cell death;
candidate genes, cloning, mapping and other aspects of molecular
genetics; and developing potential therapeutic measures such as
gene therapy and neuroprotective agents for potential
pharmaceutical therapy. While advances in these areas of retinal
degenerations will be described, there will be many new topics that
either were in their infancy or did not exist at the time of the
last RD Symposium, RD2014. These include the role of inflammation
and immunity, as well as other basic mechanisms, in age-related
macular degeneration, several new aspects of gene therapy, and
revolutionary new imaging and functional testing that will have a
huge impact on the diagnosis and following the course of retinal
degenerations, as well as to provide new quantitative endpoints for
clinical trials. The retina is an approachable part of the central
nervous system (CNS), and there is a major interest in
neuroprotective and gene therapy for CNS diseases and
neurodegenerations, in general. It should be noted that with
successful and exciting initial clinical trials in neuroprotective
and gene therapy, including the restoration of sight in blind
children, the retinal degeneration therapies are leading the way
towards new therapeutic measures for neurodegenerations of the CNS.
Many of the successes recently reported in these areas of retinal
degeneration sprang from collaborations established at previous RD
Symposia, and many of those will be reported at the RD2018 meeting
and included in the proposed volume. We anticipate the excitement
of those working in the field and those afflicted with retinal
degenerations will be reflected in the volume.
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