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Microspheres and Regional Cancer Therapy (Hardcover)
Loot Price: R7,109
Discovery Miles 71 090
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Microspheres and Regional Cancer Therapy (Hardcover)
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Microspheres and Regional Cancer Therapy takes an interdisciplinary
approach to the subject of microspheres and regional cancer
therapy. It synthesizes laboratory and clinical data to demonstrate
the utility of microsphere-based strategies in the treatment of
localized solid tumors (particularly in the liver) not amenable to
surgery and as a component of strategies for treatment of
disseminated disease. Using the same techniques that show the
deficiencies of delivery strategies involving antibodies,
liposomes, and synthetic polymers, clear evidence is presented
describing how microspheres of appropriate size can be localized in
solid tumor deposits in the liver with little exposure to other
organs. To exploit this phenomenon, the extent and nature of the
incorporation of active agents within microspheres is discussed in
relation to release, pharmacokinetics, and tumor response achieved
by intensification of therapy in the manner described. This book
will benefit laboratory-based scientists and clinicians in
pharmaceutics, pharmacology, physiology, surgical oncology, and
nuclear medicine. In addition, cancer clinicians interested in the
value of regional therapy will be able to evaluate the underlying
theory and learn the necessary methodology.
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