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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Cardiac Gene Expression - Methods and Protocols (Hardcover, 2007 ed.)
Loot Price: R2,942
Discovery Miles 29 420
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Cardiac Gene Expression - Methods and Protocols (Hardcover, 2007 ed.)
Series: Methods in Molecular Biology, 366
Expected to ship within 10 - 15 working days
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Cardiac Gene Expression: Methods and Protocols presents both
cutting-edge and established methods for studying cardiac gene
expression. The protocols provide a template for solid research,
and cover the process through screening, analysis,
characterization, and functional confirmation of novel genes or
known genes with a new function.
Section I, Cardiac Gene Expression Profiling: The Global
Perspective, discusses several different approaches to examining,
identifying, and analyzing changes in transcriptome gene
expression. Section II, Cardiac Gene Regulation: Gene-Specific mRNA
Measurement in the Myocardium, outlines more sensitive and
gene-targeted expression methods. Section III, Cardiac Gene
Regulation: Promoter Characterization in the Myocardium, provides
protocols for the study of underlying gene regulation mechanisms by
focusing on the interaction of transcription factors with their
cognate cis binding elements. Section IV, In Silico Assessment of
Regulatory cis-Elements and Gene Regulation, and Section V, Cardiac
Single Network Polymorphisms, emphasize new analytical approaches
for deciphering the functional elements buried in the 3 billion
nucleotides of the human genome and other model genomes. The
concluding section, Gene Overexpression and Targeting in the
Myocardium, highlights methods that facilitate overexpression or
cardiac-specific targeted gene deletion.
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