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Cellular Peptidases in Immune Functions and Diseases 2 (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R4,339
Discovery Miles 43 390
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Cellular Peptidases in Immune Functions and Diseases 2 (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Advances in Experimental Medicine and Biology, 477
Expected to ship within 10 - 15 working days
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Of the many special roles played by proteolytic enzymes in immune
reactions, this book addresses different aspects of membrane
peptidases, signal transduction via ligation of membrane peptidases
(especially of dipeptidyl peptidase IV/CD26 and aminopeptidase
N/CD13), and regulation of membrane peptidases in vivo and in
vitro. A number of newly discovered peptidases (including cathepsin
F, W and X, carboxypeptidase X, attractin) are described, with
special emphasis given to the role of peptidases in immune and
defense reactions and in the pathogenesis of inflammatory and other
diseases, including rheumatoid arthritis, pancreatitis, multiple
sclerosis, Alzheimer's disease and tumours of various origins. The
focus on the involvement of a selection of proteolytic enzymes in
immune reactions and diseases is a unique feature of this
multifaceted work , which combines biochemical, immunological and
clinical research reports with literary reviews of the field.
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