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Books > Medicine > Clinical & internal medicine > Rheumatology
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Side Effects of Anti-Inflammatory Drugs IV - The Proceedings of the IVth International Meeting on Side Effects of Anti-inflammatory Drugs, held in Sheffield, UK, 7-9 August 1995 (Hardcover, Partly reprinted from INFLAMMAPHARMACOLOGY, 3-4, 1997)
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Side Effects of Anti-Inflammatory Drugs IV - The Proceedings of the IVth International Meeting on Side Effects of Anti-inflammatory Drugs, held in Sheffield, UK, 7-9 August 1995 (Hardcover, Partly reprinted from INFLAMMAPHARMACOLOGY, 3-4, 1997)
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Recent concern about the adverse effects and relative risks of
anti- inflammatory therapies has been such that another meeting was
organized in the highly successful series of meetings on this
topic. Adverse effects of anti-rheumatic and anti-inflammatory
drugs are of major concern to all involved in the prescription,
care and management of rheumatic and other patients receiving these
important drugs. The IVth International Meeting on Side-Effects of
Anti-Inflammatory Drugs, held in Sheffield, UK, 7-9 August 1995,
afforded a unique opportunity to hear the latest information and
views on issues concerning the development of adverse effects from
these drugs, the management of these effects, and the development
of safer therapies. In addition to discussions on the safety
relative to efficacy of established non-steroidal and steroidal
anti-inflammatory drugs and disease-modifying agents, there was
detailed consideration of the novel cyclo-oxygenase-2 selective
NSAIDs which have recently been developed and introduced to the
clinic. Also, the side effects from therapy with biologics, notably
monoclonal antibodies and oral tolerance therapies, were
considered. Among the other highlights in the programme were:
Clinico-epidemiological studies on the adverse effects relative to
use/efficacy of established and new anti-rheumatic drugs.
Procedures for reducing the gastrointestinal adverse effects.
Mechanisms and clinical significance of adverse effects in the
gastrointestinal tract, liver, kidney, articular joints, skin and
other organs from NSAIDs. Clinical status and mechanisms of action
of the newer (third generation) of NSAIDs (e.g. etodolac,
nabumetone, meloxicam). Medico-legal aspects ofadverse effects from
anti-rheumatic drugs. The concept of conditional pharmacology' or
the disease-dependence of the toxicological and pharmacological
activity of the anti-inflammatory drugs. The papers in this book
were selected from those presented at the meeting.
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