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Biopharmaceuticals in Plants - Toward the Next Century of Medicine (Paperback)
Loot Price: R2,399
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Biopharmaceuticals in Plants - Toward the Next Century of Medicine (Paperback)
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Transgenic plants present enormous potential to become one of the
most cost-effective and safe systems for large-scale production of
proteins for industrial, pharmaceutical, veterinary, and
agricultural uses. Over the past decade, much progress has been
made with respect to the development of vaccines, antibodies, and
other therapeutic proteins. Biopharmaceuticals in Plants: Toward
the Next Century of Medicine provides a comprehensive survey of all
major aspects of the development and production of plant-made
biopharmaceuticals. Accompanied by an exhaustive list of references
to facilitate further study, this critical volume: Describes the
theory and practice of modern plant transformation techniques with
respect to nuclear and plastic genomes Outlines the steps involved
in the generation of transgenic plants Discusses the engineering of
plant virus expression vectors for transient expression of vaccine
proteins and other therapeutics in plant tissue Addresses the
significant role of glycosylation in the production of plant-made
mammalian proteins Investigates the basis of mucosal immunity using
plant-based oral vaccines Examines the scale-up of plant-derived
vaccine and therapeutic proteins in entire crops or in large batch
cell suspension cultures Explores the development of clinical
trials utilizing plant-derived biopharmaceutical proteins Evaluates
risks and biosafety concerns regarding plant-derived
pharmaceuticals The book concludes with a discussion of the future
of plant-based vaccines and other therapeutic proteins with respect
to commercial viability and as a tool to improve global public
health. Far-reaching in its scope, this text is a baseline
reference that students and researchers in a broad range of fields
such as medicine, plant science, biotechnology, crop science,
natural products chemistry, and engineering will consult regularly.
It will also serve as a useful tool for individuals and companies
seeking to invest in this dynamic area.
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