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Molecules to Medicine with mTOR - Translating Critical Pathways into Novel Therapeutic Strategies (Hardcover)
Loot Price: R4,137
Discovery Miles 41 370
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Molecules to Medicine with mTOR - Translating Critical Pathways into Novel Therapeutic Strategies (Hardcover)
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Molecules to Medicine with mTOR: Translating Critical Pathways into
Novel Therapeutic Strategies is a one-stop reference that
thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR,
also known as the mammalian target of rapamycin, is a 289-kDa
serine/threonine protein kinase that is ubiquitous throughout the
body and has a critical role in gene transcription and protein
formation, stem cell development, cell survival and senescence,
aging, immunity, tissue regeneration and repair, metabolism,
tumorigenesis, oxidative stress, and pathways of programmed cell
death that include apoptosis and autophagy. Incorporating a
translational medicine approach, this important reference
highlights the basic cellular biology of mTOR pathways, presents
the role of mTOR during normal physiologic function and disease,
and illustrates how the mechanisms of mTOR can be targeted for
current and future therapeutic treatment strategies. Coverage of
mTOR signaling includes the entire life cycle of cells that impacts
multiple systems of the body including those of nervous,
cardiovascular, immune, musculoskeletal, endocrine, reproductive,
renal, and respiratory origin.
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