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Emerging and Endemic Pathogens - Advances in Surveillance, Detection and Identification (Paperback, 2010 ed.)
Loot Price: R5,723
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Emerging and Endemic Pathogens - Advances in Surveillance, Detection and Identification (Paperback, 2010 ed.)
Series: NATO Science for Peace and Security Series A: Chemistry and Biology
Expected to ship within 10 - 15 working days
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It is a truism among biologists that an organism's phenotype is the
product of both its genotype and its environment. An organism's
genotype contains the total informational potential of the
individual, while its environment shapes the expression of the ge-
type, influences the rate of mutation and occurrence of
modifications, and ultimately determines the likelihood that the
genotype (or fractions thereof) will survive into the next
generation. In the relationship between host and pathogen,
therefore, each forms a part of the environment of the other,
mutually influencing the biology of both partners on scales ranging
from the life history of individuals to the fate of populations or
entire species. Molecular biologists working on problems in
pathogenesis generally think of the host organism as the pathogen's
environment and perhaps occasionally consider the pathogen as part
of the host's environment. However, because "environment" can be
defined at many scales, so, too, can phenotypes: if a pathogen, as
a species, is c- sidered to exist in a host, as a species, then
among its phenotypes is the nature of the pandemic disease it can
cause within the host community. The contributors to the
proceedings of this NATO Advanced Research Workshop have treated
the interplay of environment and genotype in the host-pathogen
relationship and its relationship to the problem of emerging
infectious disease at both the macroscopic and microscopic/
molecular levels along this continuum of scale (with some human
history thrown in at times for good measure).
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