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Proteases as Targets for Therapy (Hardcover)
Loot Price: R2,581
Discovery Miles 25 810
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Proteases as Targets for Therapy (Hardcover)
Series: Handbook of Experimental Pharmacology, v. 140
Expected to ship within 12 - 17 working days
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This volume is the first to combine latest information on viral,
microbial and cellular proteolytic enzymes as potential targets for
human therapeutics. Proteases control a large array of
physiological reactions, and are involved in a variety of
pathological processes for which effective medications are
currently needed and/or being sought after. Although protease
inhibitors have been investigated for many years, few have been
employed therapeutically. Recent break- through by HIV protease
inhibitors as therapeutic drugs has re-encouraged the search for
inhibitors of other proteolytic enzymes. Klaus von der Helm, who
described the first viral protease has brought leading experts
together to discuss not only the success and problems of clinical
use and continuing prospects, but to review further potential drug
targets. This volume provides detailed information and evaluations
of key viral, bacterial, fungal, and cellular proteases as
potential future drug candidates.
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