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Books > Medicine > Nursing & ancillary services > Biomedical engineering
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Peptide and Protein for Design Biopharmaceutical Applications (Hardcover)
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Peptide and Protein for Design Biopharmaceutical Applications (Hardcover)
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Peptides serve as effective drugs in the clinic today. However the
inherent drawbacks of peptide structures can limit their efficacy
as drugs. To overcome this researchers are developing new methods
to create tailor-made' peptides and proteins with improved
pharmacological properties. Design of Peptides and Proteins
provides an overview of the experimental and computational methods
for peptide and protein design, with an emphasis on specific
applications for therapeutics and biomedical research. Topics
covered include: * Computer modeling of peptides and proteins *
Peptidomimetics * Design and synthesis of cyclic peptides *
Carbohydrates in peptide and protein design * De novo design of
peptides and proteins * Medical development applications * An
extended case study - the design of insulin variants Design of
Peptides and Proteins presents the state-of-the-art of this
exciting approach for therapeutics, with contributions from
international experts. It is an essential resource for academic and
industrial scientists in the fields of peptide and protein drug
design, biomedicine, biochemistry, biophysics, molecular modelling,
synthetic organic chemistry and medicinal/pharmaceutical chemistry.
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