This volume provides an introduction to the general principles of
neuromodulation--the key neurobiological process for understanding
how the brain works. Emphasizing ion channels and biochemical
mechanisms of protein phosphorylation, the book shows how neurons
regulate their intracellular calcium concentration by modulating
the activity of certain ion channels. It goes on to explain the
function of intracellular calcium and describes some fascinating
neuromodulatory phenomena in the mammalian brain that have long
awaited the kind of mechanistic investigations possible in simpler
systems. Bridging the gap between neurochemistry and
neurophysiology, the authors make complex concepts and research
approaches comprehensible to scientists in either field.
General
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