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Books > Science & Mathematics > Chemistry > Analytical chemistry > Qualitative analytical chemistry > Magnetic resonance
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New Applications of NMR in Drug Discovery and Development (Hardcover)
Loot Price: R5,055
Discovery Miles 50 550
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New Applications of NMR in Drug Discovery and Development (Hardcover)
Series: New Developments in NMR, Volume 2
Expected to ship within 18 - 22 working days
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This book presents a review of recent developments in NMR
applications in pharmaceutical research. Consideration is given to
consolidated and emerging techniques and methods, many of which are
not yet widely applied but are likely to provide new opportunities
for drug design. The first part of the book is dedicated to the
description of NMR as a tool for the analysis of chemicals and
their interactions with targets. The next seven chapters describe
NMR approaches to investigate in vivo models of interest in drug
discovery and development, with the attention focused on anatomy,
function, metabolism and molecular-cellular aspects. Finally,
consideration is given to the application of in vivo NMR to the
identification and characterization of biomarkers with the aim of
monitoring the outcome of therapeutic intervention in selected
human diseases, including the study of drug metabolism and
toxicity. Aimed at NMR spectroscopists, pharmacologists, imaging
researchers and pharmaceutical scientists, this title is invaluable
at putting NMR in context within its role in drug discovery and
development. This resource is essential reading for those both new
and already active in these areas.
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