Lipids play an essential role in cell signaling and subcellular
structure. Systematic analysis of the total lipid structure of a
cell or organism, the lipodome, can reveal novel avenues of
therapeutic intervention and diagnosis. This analysis is best
modeled after the lessons learned from proteomics. With
contributions from pioneering researchers from the US, Europe,
Canada, Japan, and China, Functional Lipidomics introduces
lipidomics, explores the current state of the field, and provides a
comprehensive background for future groundbreaking work in this
burgeoning field.
The first book dedicated to the topic, Functional Lipidomics
first defines and introduces the field before delving deeply into
the methods, processes, analyses, and research aspects. The book
uncovers the biosynthesis, metabolism, and function of fatty acids,
acylglyerols, glycerophospholipids, sphingolipids, terpenes, and
lipids that complex with proteins. Taking both academic and
industrial perspectives, the contributors elaborate upon
cutting-edge approaches to lipid analysis, diagnostic approaches
using lipid and lipid-binding protein patterns, and the therapeutic
significance of targeting proteins involved with the lipid
signaling pathway.
Functional Lipidomics elucidates state-of-the-art strategies and
techniques that enable us to understand biochemical patterns
related to disease states, develop new targets for drug design, and
identify important markers of a developmental stage, pathological
condition, or disease treatment.
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