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Practical Bioinformatician, The (Paperback)
Loot Price: R2,645
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Practical Bioinformatician, The (Paperback)
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Computer scientists have increasingly been enlisted as
"bioinformaticians" to assist molecular biologists in their
research. This book is a practical introduction to bioinformatics
for these computer scientists. The chapters are in-depth
discussions by expert bioinformaticians on both general techniques
and specific approaches to a range of selected bioinformatics
problems. The book is organized into clusters of chapters on the
following topics:* Overview of modern molecular biology and a broad
spectrum of techniques from computer science - data mining, machine
learning, mathematical modeling, sequence alignment, data
integration, workflow development, etc.* In-depth discussion of
computational recognition of functional and regulatory sites in DNA
sequences.* Incisive discussion of computational prediction of
secondary structure of RNA sequences.* Overview of computational
prediction of protein cellular localization, and selected
discussions of inference of protein function.* Overview of methods
for discovering protein-protein interactions.* Detailed discussion
of approaches to gene expression analysis for the diagnosis of
diseases, the treatment of diseases, and the understanding of gene
functions.* Case studies on analysis of phylogenies, functional
annotation of proteins, construction of purpose-built integrated
biological databases, and development of workflows underlying the
large-scale-effort gene discovery.
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