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Renal Medullary Circulation (Paperback) Loot Price: R748
Discovery Miles 7 480
Renal Medullary Circulation (Paperback): Louise Evans, Allen Cowley

Renal Medullary Circulation (Paperback)

Louise Evans, Allen Cowley

Series: Colloquium Series on Integrated Systems Physiology: From Molecule to Function

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Loot Price R748 Discovery Miles 7 480 | Repayment Terms: R70 pm x 12*

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The two kidneys of mammalian organisms receive around 25 % of the cardiac output at rest, of which only 7 % is distributed to the renal medulla. Despite the low blood flow to the renal medulla, small changes in perfusion to the region can have profound effects on urine-concentrating ability and the excretion of sodium, which in turn affects the chronic regulation of body fluid volumes and arterial blood pressure. Importantly, we know that if blood flow to the renal medulla is not tightly regulated, sodium and water homeostasis is impaired and medullary hypoxia develops. The resultant injury inevitably reduces urine concentrating ability and leads to hypertension. This book will discuss the variety of mechanisms that mammalian organisms have developed to ensure that renal medullary blood flow and oxygen levels are precisely regulated. This book will focus on the unique anatomical arrangement of the medullary circulation, the functional roles of medullary blood flow, as well as the experimental techniques used to assess medullary blood flow and the insight that these studies have provided. The hormonal and non-hormonal control of medullary blood flow will be considered and finally the impact of reduced medullary blood flow on blood pressure is discussed.

General

Imprint: Morgan & Claypool Publishers
Country of origin: United States
Series: Colloquium Series on Integrated Systems Physiology: From Molecule to Function
Release date: August 2015
First published: 2010
Authors: Louise Evans • Allen Cowley
Dimensions: 235 x 191 x 11mm (L x W x T)
Format: Paperback
Pages: 104
ISBN-13: 978-1-61504-228-9
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General
Books > Medicine > Clinical & internal medicine > Renal medicine > General
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LSN: 1-61504-228-8
Barcode: 9781615042289

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