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Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications - Proceedings of the 6th International Conference on Sodium Calcium Exchange (Hardcover, 2013 ed.)
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Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications - Proceedings of the 6th International Conference on Sodium Calcium Exchange (Hardcover, 2013 ed.)
Series: Advances in Experimental Medicine and Biology, 961
Expected to ship within 12 - 17 working days
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This book reports the text of the lectures of the 6th International
Conference on Sodium Calcium Exchange held in Lacco Ameno in the
Island of Ischia in the Gulf of Naples, Italy, from October 1 to
October 5, 2011. The present book uncovers the most striking new
findings on NCX that emerged since the previous Conference on
Sodium Calcium Exchange, such as the structural dissection of the
molecular determinants of Ca2+ sensitivity of the exchanger, the
epigenetic regulation of ncx1 gene, the molecular identification of
the mitochondrial Sodium Calcium Exchanger, and the discovery of
NCX in unexpected anatomical locations such as the female
reproductive tract. The book is organized into 11 parts covering
NCX structural aspects, genetic and epigenetic regulation,
regulatory mechanisms, subcellular localization in mitochondria,
involvement in neurodegenerative diseases and in immune regulation,
and the role of the cardiovascular and endocrine systems, as well
as diabetes in physiology and pathophysiology. Selected chapters of
the book are also devoted to the interaction of NCKX and other ion
channels and transporters with NCX, like ASICs, TRPM, and NHE.
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