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Proteomics of Peroxisomes - Identifying Novel Functions and Regulatory Networks (Hardcover, 1st ed. 2018)
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Proteomics of Peroxisomes - Identifying Novel Functions and Regulatory Networks (Hardcover, 1st ed. 2018)
Series: Subcellular Biochemistry, 89
Expected to ship within 10 - 15 working days
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This new edited volume in the Springer Subcellular Biochemistry
Series presents a comprehensive, state-of-the-art overview of the
proteomics of peroxisomes derived from mammalian, Drosophila,
fungal, and plant origin, and contains contributions from leading
experts in the field. The development of sensitive proteomics and
mass spectrometry technologies, combined with bioinformatics
approaches now allow the identification of low-abundance and
transient peroxisomal proteins and permits to identify the complete
proteome of peroxisomes, with the consequent increase of our
knowledge of the metabolic and regulatory networks of these
important cellular organelles. The book lines-up with these
developments and is organized in four sections including: (i) mass
spectrometry-based organelle proteomics; (ii) prediction of
peroxisomal proteomes; (iii) analysis of peroxisome proteome
interaction networks; and (iv) peroxisomes in relation to other
subcellular compartments. The editor Luis A. del Rio is Professor
ad honorem of the Spanish National Research Council (CSIC) in the
Group of Antioxidants, Free Radicals and Nitric Oxide in
Biotechnology, Food and Agriculture, Department of Biochemistry and
Cell & Molecular Biology of Plants, at the Estacion
Experimental del Zaidin, Granada, Spain. Del Rio's research group
focuses on the metabolism of reactive oxygen species (ROS),
reactive nitrogen species (RNS) and antioxidants in plant
peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in
plant cell signalling. The editor Michael Schrader is Professor of
Cell Biology & Cytopathology in the Department of Biosciences
at the University of Exeter, UK. Using mammalian peroxisomes as
model organelles, Prof. Schrader and his team aim to unravel the
molecular machinery and signalling pathways that mediate and
regulate the formation, dynamics and abundance of these medically
relevant cellular compartments.
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