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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - Volume 1 Molecular Mechanisms (Hardcover, New)
Loot Price: R3,762
Discovery Miles 37 620
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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - Volume 1 Molecular Mechanisms (Hardcover, New)
Expected to ship within 12 - 19 working days
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Understanding the importance and necessity of the role of autophagy
in health and disease is vital for the studies of cancer, aging,
neurodegeneration, immunology, and infectious diseases.
Comprehensive and forward thinking, these books offer a valuable
guide to both cellular processes while inciting researchers to
explore their potentially important connections. Considering that
autophagy is associated with numerous biological processes,
including cellular development and differentiation, cancer (both
antitumor and protumor functions), immunity, infectious diseases,
inflammation, maintenance of homeostasis, response to cellular
stress, and degenerative diseases such as Alzheimer's, Parkinson's,
Huntington's, amyotrophic lateral sclerosis, and prion diseases,
there is a great need to understanding its role. Cell homeostasis
is achieved by balancing biosynthesis and cellular turnover. In
spite of the increasing importance of autophagy in various
pathophysiological situations (conditions) mentioned above, this
process remains underestimated and overlooked. As a consequence,
its role in the initiation, stability, maintenance, and progression
of these and other diseases (e.g., autoimmune disease) remains
poorly understood. Volumes in the Series Volume 1: Molecular
Mechanisms. Elucidates autophagy's association with numerous
biological processes, including cellular development and
differentiation, cancer, immunity, infectious diseases,
inflammation, maintenance of homeostasis, response to cellular
stress, and degenerative diseases such as Alzheimer's, Parkinson's,
Huntington's, amyotrophic lateral sclerosis, and prion diseases.
Volume 2: Role in General Diseases. Describes the various aspects
of the complex process of autophagy in a myriad of devastating
human diseases, expanding from a discussion of essential autophagic
functions into the role of autophagy in proteins, pathogens,
immunity, and general diseases. Volume 3: Role in Specific
Diseases. Explores the role of autophagy in specific diseases and
developments, including: Crohn's Disease, Gaucher Disease,
Huntington's Disease, HCV infection, osteoarthritis, and liver
injury, with a full section devoted to in-depth exploration of
autophagy in tumor development and cancer, as well as the
relationship between autophagy and apoptosis. Volume 4: Mitophagy.
Presents detailed information on the role of mitophagy, the
selective autophagy of mitochondria, in health and disease, by
delivering an in-depth treatment of the molecular mechanisms
involved in mitophagy initiation and execution, as well as the role
of mitophagy in Parkinson Disease, cardiac aging, and skeletal
muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively
describes the role of autophagy in human diseases, delivering
coverage of the antitumor and protumor roles of autophagy; the
therapeutic inhibition of autophagy in cancer; and the duality of
autophagy's effects in various cardiovascular, metabolic, and
neurodegenerative disorders. Volume 6: Regulation of Autophagy and
Selective Autophagy. Provides coverage of the mechanisms of
regulation of autophagy; intracellular pathogen use of the
autophagy mechanism; the role of autophagy in host immunity; and
selective autophagy. Volume 7: Role of Autophagy in Therapeutic
Applications. Provides coverage of the latest developments in
autophagosome biogenesis and regulation; the role of autophagy in
protein quality control; the role of autophagy in apoptosis;
autophagy in the cardiovascular system; and the relationships
between autophagy and lifestyle. Volume 8: Autophagy and Human
Diseases. Reviews recent advancements in the molecular mechanisms
underlying a large number of genetic and epigenetic diseases and
abnormalities, and introduces new, more effective therapeutic
strategies, in the development of targeted drugs and programmed
cell death, providing information that will aid on preventing
detrimental inflammation. Volume 9: Necrosis and Inflammation in
Human Diseases. Emphasizes the role of Autophagy in necrosis and
inflammation, explaining in detail the molecular mechanism(s)
underlying the formation of autophagosomes, including the
progression of Omegasomes to autophagosomes.
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