Pediatric Cancer, Volume 2 - Teratoid/Rhabdoid, Brain Tumors, and Glioma (Hardcover, 2012 ed.)

A general introduction to the principles of diagnosis and treatment of children with brain tumors is presented. Molecular characterization of solid tumors is also presented. Molecular pathways provide putative targets for new therapies. High resolution magic spinning NMR spectroscopy is explained, which is used to determine metabolic profiles for small pieces of intact tissue and whole cells in culture. The differences between adult and pediatric brain tumors are outlined. It is emphasized that pediatric low-grade gliomas need lower doses of antidrugs such as cisplatin/etoposide. It is explained that tumor suppressor genes and oncogenes play a crucial role in the development and progression of human malignancies, including those in children. Neurofibromatosis type-1 is a common genetic disorder with a high prevalence in CNS abnormalities including tumors in children; which is discussed in detail. Various neuroradiological imaging modalities in children with leukemia are detailed. Also are detailed results of clinical trials in pediatric brain tumors, such as medulloblastoma, ependymoma, craniopharyngioma, low-grade glioma, high-grade glioma, brainstem glioma, and germ cell tumors, using radiotherapy. Considering the clinical importance of epilepsy in the primary brain tumors in children, its symptoms, diagnosis, and treatments (surgery and antiepileptic drugs) are discussed.

General

Imprint:	Springer
Country of origin:	Netherlands
Series:	Pediatric Cancer, 2
Release date:	March 2012
First published:	2012
Editors:	M. A. Hayat
Dimensions:	254 x 178 x 25mm (L x W x T)
Format:	Hardcover
Pages:	352
Edition:	2012 ed.
ISBN-13:	978-9400729568
Categories:	Books > Medicine > Surgery > Surgical oncology Books > Medicine > Clinical & internal medicine > Paediatric medicine > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	9400729561
Barcode:	9789400729568

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