Presenting contributions by 66 experts representing 13
countries, Volume 10 of the series Stem Cells and Cancer Stem Cells
synthesizes current understanding of the causes, diagnosis, and
therapy of major human diseases and debilitating tissue and organ
injuries, using cell-based treatment. This volume presents
contemporary research into generation, preservation, and uses of
stem cells in fighting disease and tissue/organ injuries.
The contents of the volume are organized into five sections.
Mesenchymal Stem Cells section includes chapters on the use of stem
cells in bone regeneration, studies and trials of stem cells in
autoimmune diseases, and differences between adipose tissue-derived
mesenchymal stem cells and bone marrow-derived mesenchymal stem
cells as regulators of immune response. Induced Pluripotent Stem
Cells section offers chapters on drug discovery using human
IPSC-based disease models, and on generation of antigen-specific
lymphocytes from IPSCs. Neural Cells and Neural Stem Cells section
discusses use of bacterial artificial chromosomes in the genetic
identification of stem cell-derived neural cell types, and use of
moderate low temperature to preserve the stemness of neural stem
cells. The section, Role of Stem Cells in Disease, discusses stem
cell support in high-dose chemotherapy of Non-Hodgkin s Lymphomas;
potential targets for drug resistant leukemic stem cells, bone
marrow stem cell therapies for diabetes mellitus. This section also
discusses the use of stem cells in treating thyroid, breast and
bone cancers, hempophilia and Parkinson s Disease. The section,
Stem Cell Transplantation, includes chapters on reducing fungal
infection in allogenic stem cell transplantation patients, use of
Bulsufan/Fludarabine for conditioning in haematopoietic stem cell
transplantation, and interleukin-7 receptor alpha polymorphisms in
allogeneic stem cell transplantation.
The editor, M.A. Hayat, is a Distinguished Professor in the
Department of Biological, Sciences at Kean University, Union, New
Jersey, USA.
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